Thu nhận và tính chất của hydroxyapatit có kích thước nano từ xương cá

Abstract

     Fish bones are reported to be abundant raw materials for production of hydroxyapatite (HA), which is also found as a main component of human bones and teeth. In this study, hydroxyapatite nanoparticles were prepared from three fish bones including Barramundi (Lates calcarifer), Red Tilapia (Oreochromis sp.) and Tilapia (Oreochoromis niloticus) by a two-step thermal treatment. Firstly, fish by-products were boiled with water for 2h to remove organic components and obtained raw bones. Secondly, these bones were calcinated at a range of 500 – 900ºC for 1 – 3h to recover HA nanoparticles. From XRD and FTIR spectra and SEM images, all HA nanoparticles have a high purity and porousity. For Barramundi bones, HA with a size of 30 – 50 nm was obtained by calcinated at 700ºC for 2 h. This recovery method is facile and efficient and can be scale-up easily. Moreover, these biological HA nanoparticles have many potential applications in food, medicine and pharmacy.

Keywords: Seafood by-products, nanohydroxyapatite, fish bone, thermal treatment